Liv Tyler is set to star in medical drama The Side Effect.

The Lord of the Rings actress will play a woman named Catherine Rigby who spends several months alone in space for a global pharmaceutical company, only to find herself inexplicably pregnant in the film, set to be helmed by Ti West. Ted Hope and Peter Phok will produce the picture.

"West is a super-talented, exciting young filmmaker. The role of Rigby is a fantastic character within a great thriller and I am looking forward to sinking my teeth into the part," Liv said, commenting on the role.

Ti is best known for horror films - including Cabin Fever 2: Spring Fever and The House of the Devil - and he says his experience will play part in the new movie: "Although it is still somewhat of a horror film, it is much more psychological than any of my previous efforts. It was essential that I find an actress who could portray a wide range of emotion and always earn the audience's sympathy no matter what the situation. As soon as I sat down with Liv, it was obvious she was the one."